The Telencephalon Saved by TLC

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The Telencephalon Saved by TLC

The telencephalon is one of the most complex parts of the brain, and its patterning is still poorly understood. In this issue of Neuron, describe a novel Wnt antagonist Tlc, a member of the secreted Frizzled-related protein (sFrp) family. Secreted from the anterior boundary of the zebrafish neural plate, Tlc appears to protect the telencephalon from obliteration by a more caudal neural Wnt signal.

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ژورنال

عنوان ژورنال: Neuron

سال: 2002

ISSN: 0896-6273

DOI: 10.1016/s0896-6273(02)00779-1